Neurotransmitters+Involved+in+Short+Term+Memory

**Glutamate** This neurotransmitter is widely considered the as one of the most important excitatory and signaling neurotransmitters present within the brain. It's glutamate that the Ampakine drugs interact with in order to increase short term memory. How cells respond to the presence of glutamate is mostly how the increase in brain activity due to the presence of drugs such as the Ampakine group is explained. A binding occurs when glutamate is activated resulting in the release of activating proteins.


 * Acetylcholine **

This Neurotransmitter is similar to the glutamate in that it acts in an excitatory manner at neuromuscular junctions. Phenserine, Aricept and Exelon are the drugs which act upon this neurotransmitter to treat people with disease that result in impairment of their short term memory. Ach plays a vital role in brain chemistry and in particular in the sensory perceptions. The cholinergic system in the brain is responsible for the production of Ach, damage to this region of the brain has been shown to affect short term memory in humans and cause the brain disease known as Alzheimer's. An increase in performance of Ach that can be promoted through administration of the previously mentioned three drugs, Phenserine, Aricept and Exelon, results in an overall increase in efficiency of short term and spatial memory.